陈向涛，副教授

研究方向：中药及活性成分改善学习记忆的研究

电子邮箱：陈向涛@ahmu.edu.cn

办公室：知行楼B1206

教育经历：

(1) 2001/09-2005/06， 维多利亚老品牌vic3308，维多利亚老品牌vic3308，博士

(2) 1992/09-1995/06， 安徽中医药大学，中医临床学院，硕士

(3)1987/09-1992/06，  安徽中医药大学，中医临床学院，学士

工作经历：

(1) 2013/07至今，维多利亚老品牌vic3308，维多利亚老品牌vic3308，副教授

(2) 2008/09-2011/09，美国加州大学伯克利，分子与遗传学院，访问学者

(3) 2006/04-2008/08，中国科学技术大学， 生命科学学院， 博士后

(4) 1995/07-2013/08 安徽中医药大学，教师

科研项目：

(1)国家自然科学基金委员会,面上项目, 82274124, “芳香开窍”中药石菖蒲改善学习记忆功能的內嗅皮层-海马神经环路机制研究, 2023-01-01至2026-12-31, 52万元,在研,主持

(2)国家自然科学基金委员会,面上项目, 81673624, β-细辛醚通过调控NMDA受体兴奋性和突触重塑抗阿尔茨海默病的作用机制研究, 2017.01至2020.12, 52万元,已结题,主持

发表论文情况：

1.Lanxiang Yin, Xintong Yuan, Jiahui Yu, Xuemin Ren, Hongqin Zhan, Yunyan Ye, Zixuan Wang, Xiangtao Chen#, β-asarone relieves Parkinson's disease through reducing intracellular Ca2+ in PINK1 mutant Drosophila melanogaster [J].Eur J Pharmacol, 2025 15:987:177155

2.Yanyan Xiao, Chenglin Yang, Nana Si, Tao Chu, Jiahui Yu, Xintong Yuan, Xiang-Tao Chen#. Epigallocatechin-3-gallate Inhibits LPS/AβO-induced Neuroinflammation in BV2 Cells through Regulating the ROS/TXNIP/NLRP3 Pathway [J]. Journal of Neuroimmune Pharmacology, 2024, 19(1): 31.

3.Rong-Xin Zou, Xiaozhen Gu, Chenqing Huang, Hui-Li Wang, Xiang-Tao Chen#. Pb exposure impairs learning and memory abilities by inhibiting excitatory projection neuro-circuit of the hippocampus in mice [J]. Toxicology, 2024, 502: 153717.

4.Juanjuan Liu, Xiaozhen Gu, Rongxin Zou, Wenping Nan, Shaohua Yang, Hui-Li Wang, Xiang-Tao Chen#. Phytohormone abscisic acid improves spatial memory and synaptogenesis involving NDR1/2 kinase in rats [J]. Frontiers in pharmacology, 2018, 9: 1141.

5.Haoyu Liu, Ruiqing Zhou, Lanxiang Yin, Nana Si, Chenglin Yang, Chengqing Huang, Rongrong Wang, Xiangtao Chen#. β-asarone prolongs sleep via regulating the level of glutamate in the PVN [J]. Biochemical and Biophysical Research Communications, 2023, 665: 71-7.

6.Shu Ai, Danyang Li, Xiaozhen Gu, Yi Xu, Yi Wang, Hui-Li Wang, Xiang-Tao Chen. Profile of N6-methyladenosine of Pb-exposed neurons presents epitranscriptomic alterations in PI3K-AKT pathway-associated genes [J]. Food and Chemical Toxicology, 2023, 178: 113821.

7.Rong-Xin Zou, Xiaozhen Gu, Jin-Jun Ding, Tiandong Wang, Nanxi Bi, Kang Niu, Mengmeng Ge, Xiang-Tao Chen#, Hui-Li Wang#. Pb exposure induces an imbalance of excitatory and inhibitory synaptic transmission in cultured rat hippocampal neurons [J]. Toxicology in Vitro, 2020, 63: 104742.

8.Ruiqing Zhou, Jing Zhao, Danyang Li, Yao Chen, Yanyan Xiao, Anni Fan, Xiang-Tao Chen#, Hui-Li Wang#. Combined exposure of lead and cadmium leads to the aggravated neurotoxicity through regulating the expression of histone deacetylase 2 [J]. Chemosphere, 2020, 252: 126589.